PVE
New zone. Zamora. Lore wise so much took place in this region. You also have 2 major citys. Shadizar (the wicked) city of thieves and Arenjun. You also have yezed home of the spider god. Perfect for a new raid area or hoc type 6man instances. Both maybe The tower of the elephant could be a great 6 man.
It would i think have to be a rather large area though. Bigger then turan if you wanted to do it right. IMO anyways.
PVP
New map. Tarantia commons. Rooftop and alleyways would make pvp pretty intense. Granted i havnt pvp;d in a long time but i think it would be fun.