Short answer ... Yes.
Long answer... it gets a bit more complicated than that. It depends on why you disliked skyrim and it depends on what you're looking for in ESO. Personally, I enjoy the elder scrolls lore and setting, but honestly I don't give a crap about that kind of stuff in an MMO as long as it isn't so bad it is distracting. The only thing that I feel transfers from Elder Scrolls single player to ESO is the lore and the nature in which you discover things to do. In Morrowind, Oblivion, and Skyrim, I would set off from a town to do one specific thing that was let's say about 4km away. As I was heading towards that objective I would pass by a cave needed exploring, nirnroots that needed picking, a bandit camp that needed cleansing, a unicorn protected by trolls that needed killing, or a brand new quest giver that needed saving. Next thing I knew, it would be 6 hours later and I still hadn't even made it to my original objective. That is ESO and that is why I think the single player PVE in this game is going to be so much better than the traditional HUB city quest giver scenario that most MMOs use. You can set off in any direction in ESO without an idea of what you are trying to accomplish and you will run into a lot of things to do.
Aside from the nature of exploration and quests, I do not think ESO shares many similarities with the single player experience. Combat is different besides the quick attack, power attack, and block mechanics. You have two weapon sets with 6 active abilities you can mix and match per weapon. Add to that a quick slot item that can be changed on the fly which may include potions, food, siege weapons, and probably a few others I am unaware of. It doesn't sound like a lot (especially before lvl 15 when you only have one weapon set) but the fact that you are aiming your attacks with the mouse (basically like right click was permanently held down in AoC) and using mouse clicks to attack and block completely changes the standard MMO formula for me.
I find I can't really express the exact reason why having a left click quick attack, left click hold power attack, right click block, left and right click at the same time interrup bash, and double tap dodge changes the experience for me but it makes it feel like you are in more control of your character. It feels like your attacks are more of an actual extension of what you are controlling instead of in AoC's case where you're basically picking an ability and pressing some direction keys to complete it. For some reason pressing a single key or a series of keys to attack someone is no where near as engaging as running up behind someone in PVP and mashing the left click down to perform a power attack that drops them to the ground and kills them.
Outside of the combat mechanics, I feel the PVP can be very engaging. I logged into the realm vs realm vs realm zone with my faction being crushed. We had about 3 keeps and were getting destroyed. I don't think I made the difference but all a sudden things started to turn. Yes there was a zerg but I followed them to the enemy keep and we deployed our ballistas and tore down an enemy faction keep wall. The enemies retreated to the central keep itself and I set up my ballista taking them out up on their walls while they fired down on us with ranged attacks. Someone in our zerg had a battering ram so we were attacking their keep door trying to keep the battering ram guy alive with heals while there was massive chaos all around with enemies trying desperately to stop us. A few minutes later we wiped them out and had a keep as most people started quickly repairing walls and doors while the zerg moved on to another keep. A couple of hours later and we had 2/3 of the total keeps to ourselves and were fighting frantically to hold on to it while the enemy was doing crazy back line attacks which would cut us off from quick travel across the map. Add to that the fact that you can run endless PVP single player missions to scout out an area, or bring a group and take smaller towns and I think the PVP will stay fresh no matter how many people you roll with.
The only unknown for me right now is what end game PVE will be like. From what I have seen so far, I am willing to shell out 60 bucks +15 a month for however months to find out.